Tag Archives: PCSK9 inhibitors

FDA Approval: Repatha (evolocumab) injection

The U.S. Food and Drug Administration yesterday approved Repatha (evolocumab) injection for some patients who are unable to get their low-density lipoprotein (LDL) cholesterol under control with current treatment options.

Repatha, the second drug approved in a new class of drugs known as PCSK9 inhibitors, is approved for use in addition to diet and maximally-tolerated statin therapy in adult patients with heterozygous familial hypercholesterolemia (HeFH), homozygous familial hypercholesterolemia (HoFH), or clinical atherosclerotic cardiovascular disease, such as heart attacks or strokes, who require additional lowering of LDL cholesterol.

The most common side effects of Repatha include nasopharyngitis, upper respiratory tract infection, flu, back pain, and reactions such as redness, pain, or bruising where the injection is given. Allergic reactions, such as rash and hives, have been reported with the use of Repatha. Patients should stop using Repatha and get medical help if they experience symptoms of a serious allergic reaction.

For more information, please visit: Repatha

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FDA OKs First of New Class of Cholesterol Drugs

Praluent for people with prior history of heart attack or stroke who’ve already tried a statin

FRIDAY, July 24, 2015 (HealthDay News) — The U.S. Food and Drug Administration on Friday approved Praluent, the first of a powerful new class of injected, cholesterol-lowering drugs that experts believe could change cardiovascular care.

Praluent (alirocumab) sharply cuts levels of LDL (“bad”) cholesterol, and is one of a group of newly developed drugs called PCSK9 inhibitors, the FDA explained in a news release.

The drug is only approved for patients with heart disease and a history of heart attack or stroke “who require additional lowering of LDL cholesterol” in addition to taking a statin drug and adopting a healthy diet, the agency said.

For more information please visit FDA website.

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